Evidence Review of E-cigarettes and Heated Tobacco Products 2018

Evidence Review of E-cigarettes and Heated Tobacco Products 2018

Public Health England (PHE) has issued a detailed 243 page report examining the health implications of e-cigarette use. Titled Evidence Review of E-cigarettes and Heated Tobacco Products 2018, this is the second report on the topic of e-cigarettes to be issued by a major independent health body within the past few weeks. On January 23rd the National Academy of Sciences, Engineering and Medicine issued their long awaited report titled “The Public Health Consequences of E-cigarettes.”

These products pose a far less risk to health when compared to cigarette smoking and can save lives if current smokers can be persuaded to use them in place of the deadly cigarette.

While not totally risk free, the PHE report estimates that they may be 95% less dangerous than regular cigarette smoking.

Public Health England’s overall conclusions are:  

  • e-cigarette use is associated with improved quit success rates over the last year and an accelerated drop in smoking rates across the country
  • many thousands of smokers incorrectly believe that vaping is as harmful as smoking; around 40% of smokers have not even tried an e-cigarette
  • there is much public misunderstanding about nicotine (less than 10% of adults understand that most of the harms to health from smoking are not caused by nicotine)
  • the use of e-cigarettes in the UK has plateaued over the last few years at just under 3 million
  • the evidence does not support the concern that e-cigarettes are a route into smoking among young people (youth smoking rates in the UK continue to decline, regular use is rare and is almost entirely confined to those who have smoked)

Perhaps the most important aspect of PHE’s report is its assessment of the health consequences of e-cigarette use.   The report calculated that e-cigarettes represent only a fraction of the risk posed by smoking standard combustible cigarettes.

  • One assessment of the published data on emissions from cigarettes and e-cigarettes calculated the lifetime cancer risks. It concluded that the cancer potencies of e-cigarettes were largely under 0.5% of the risk of smoking.
  • Comparative risks of cardiovascular disease and lung disease have not been quantified but are likely to be also substantially below the risks of smoking. Among e-cigarette users, two studies of biomarker data for acrolein, a potent respiratory irritant, found levels consistent with non-smoking levels.
  • There have been some studies with adolescents suggesting respiratory symptoms among e-cigarette experimenters. However, small scale or uncontrolled switching studies from smoking to vaping have demonstrated some respiratory improvements.
  • E-cigarettes can release aldehydes if e-liquids are overheated, but the overheating generates an aversive taste.
  • To date, there is no clear evidence that specific flavourings pose health risks but there are suggestions that inhalation of some could be a source of preventable risks.
  • To date, the levels of metals identified in e-cigarette aerosol do not give rise to any significant safety concerns, but metal emissions, however small, are unnecessary.
  • Biomarkers of exposure assessed to date are consistent with significant reductions in harmful constituents and for a few biomarkers assessed in this chapter, similar levels to smokers abstaining from smoking or non-smokers were observed.
  • One study showed no reductions across a range of biomarkers for dual users (either for nicotine replacement therapy or e-cigarette dual users).
  • To date, there have be en no identified health risks of passive vaping to bystanders.
  • Reporting of some academic studies has been misleading.

The National Academy of Sciences recently published review reached similar conclusions regarding the health effects of e-cigarettes for adults. These two reports stand in sharp contrast to the 2016 report issued by the US Surgeon General in which he stated: “E-cigarette use among U.S. youth and young adults is now a major public health concern.” While no one thinks kids should be permitted to use e-cigarettes, and policies are needed to ensure kids do not have access to them, the reports of the NAS and PHE are clear when it comes to adult use — these products pose a far less risk to health when compared to cigarette smoking and can save lives if current smokers can be persuaded to use them in place of the deadly cigarette. While not totally risk free, the PHE report estimates that they may be 95% less dangerous than regular cigarette smoking.

A copy of the full 243 page report of Public Health England can be downloaded from their web site:

https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/679262/Evidence_review_of_e-cigarettes_and_heated_tobacco_products_2018.pdf